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Maaike H Oosterveer Selected Research

Glucose-6-Phosphatase (Glucose 6 Phosphatase)

8/2022High childhood serum triglyceride concentrations associate with hepatocellular adenoma development in patients with glycogen storage disease type Ia.
11/2021Hepatocyte-specific glucose-6-phosphatase deficiency disturbs platelet aggregation and decreases blood monocytes upon fasting-induced hypoglycemia.
11/2020Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a.
1/2020Glycogen storage disease type 1a is associated with disturbed vitamin A metabolism and elevated serum retinol levels.
12/2017Hepatocytes contribute to residual glucose production in a mouse model for glycogen storage disease type Ia.
1/2017Clinical and biochemical heterogeneity between patients with glycogen storage disease type IA: the added value of CUSUM for metabolic control.
12/2010Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1.

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Maaike H Oosterveer Research Topics

Disease

7Glycogen Storage Disease (Glycogenosis)
11/2021 - 12/2010
6Metabolic Diseases (Metabolic Disease)
01/2022 - 06/2012
5Atherosclerosis
01/2020 - 10/2010
4Hepatorenal form of glycogen storage disease
08/2022 - 01/2017
4Hypoglycemia (Reactive Hypoglycemia)
01/2022 - 01/2021
3Liver Diseases (Liver Disease)
11/2021 - 08/2012
3Non-alcoholic Fatty Liver Disease
11/2020 - 02/2017
3Type 2 Diabetes Mellitus (MODY)
12/2019 - 10/2010
3Obesity
07/2015 - 12/2011
2Liver Cell Adenoma (Hepatocellular Adenoma)
08/2022 - 11/2021
2Hypertriglyceridemia
11/2021 - 01/2021
2Dyslipidemias (Dyslipidemia)
01/2021 - 03/2010
2Osteoporosis
01/2020 - 01/2017
2Inflammation (Inflammations)
01/2020 - 12/2011
2Neoplasms (Cancer)
01/2019 - 01/2016
2Metabolic Syndrome (Dysmetabolic Syndrome X)
07/2015 - 01/2014
2Insulin Resistance
08/2012 - 09/2008
1Carcinoma (Carcinomatosis)
11/2021
1Hemorrhage
11/2021
1Fatty Liver
01/2021
1Glycogen Storage Disease IB
01/2021
1Multiple Acyl Coenzyme A Dehydrogenase Deficiency
01/2021
1Inborn Errors Metabolism (Inborn Errors of Metabolism)
01/2021
1Hepatomegaly
11/2020
1Fibrosis (Cirrhosis)
01/2020
1Sudden Death
12/2017
1Adenoma (Adenomas)
01/2017
1Metabolic Bone Diseases (Osteopenia)
01/2017
1Liver Neoplasms (Liver Cancer)
01/2016
1Carcinogenesis
01/2016
1Hyperinsulinism (Hyperinsulinemia)
01/2014
1Hyperglycemia
01/2014
1Disease Progression
01/2013

Drug/Important Bio-Agent (IBA)

8Glucose (Dextrose)FDA LinkGeneric
01/2022 - 10/2010
7Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA
08/2022 - 12/2010
4Triglycerides (Triacylglycerol)IBA
08/2022 - 01/2017
4Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
01/2020 - 10/2014
3CarbohydratesIBA
11/2020 - 09/2008
3CholesterolIBA
01/2017 - 08/2012
2IsotopesIBA
01/2022 - 09/2008
2Hypoglycemic Agents (Hypoglycemics)IBA
11/2021 - 01/2021
2Carrier Proteins (Binding Protein)IBA
11/2020 - 12/2010
2LipidsIBA
11/2020 - 12/2011
2Bile Acids and Salts (Bile Acids)IBA
12/2019 - 08/2012
2Pharmaceutical PreparationsIBA
01/2013 - 08/2012
2Liver X ReceptorsIBA
01/2013 - 12/2010
1Proteins (Proteins, Gene)FDA Link
11/2021
1CorticosteroneIBA
11/2021
1Adenosine Diphosphate (ADP)IBA
11/2021
1Prothrombin (Factor II)IBA
11/2021
1VLDL LipoproteinsIBA
01/2021
1Starch (Cornstarch)IBA
01/2021
1empagliflozinIBA
01/2021
1Nonesterified Fatty Acids (NEFA)IBA
01/2021
13-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)IBA
01/2021
1KetonesIBA
01/2021
1GlycogenIBA
11/2020
1Messenger RNA (mRNA)IBA
01/2020
1LDL Receptors (LDL Receptor)IBA
01/2020
1Co-Repressor ProteinsIBA
01/2020
1Vitamin A (Retinol)FDA LinkGeneric
01/2020
1LigandsIBA
01/2019
1FructoseIBA
01/2019
1Transcription Factors (Transcription Factor)IBA
01/2019
1Hormones (Hormone)IBA
12/2018
1GlucocorticoidsIBA
12/2018
1CORT118335IBA
12/2018
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
12/2018
1Sucrose (Saccharose)IBA
02/2017
1Lactic Acid (Lactate)FDA LinkGeneric
01/2017
1Uric Acid (Urate)IBA
01/2017
1Glutamic Acid (Glutamate)FDA Link
01/2016
1Transaminases (Aminotransferases)IBA
01/2016
1Pyruvic Acid (Pyruvate)IBA
01/2016
1Glutamine (L-Glutamine)FDA Link
01/2016
1Oxaloacetic Acid (Oxalacetic Acid)IBA
01/2016
1Volatile Fatty AcidsIBA
07/2015
1Dietary FiberFDA Link
07/2015
1Lysine (L-Lysine)FDA Link
10/2014
1Insulin (Novolin)FDA Link
01/2014
1Fatty Acids (Saturated Fatty Acids)IBA
08/2012
1NAD (NADH)IBA
06/2012
1nicotinamide-beta-ribosideIBA
06/2012
1Sirtuin 1IBA
06/2012
1EndocannabinoidsIBA
12/2011
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
12/2011
16alpha-ethyl-23(S)-methylcholic acidIBA
12/2011
1Liver GlycogenIBA
12/2010
1Blood Glucose (Blood Sugar)IBA
03/2010

Therapy/Procedure

2Glycemic Control
11/2021 - 01/2021
1Precision Medicine
01/2017
1Therapeutics
01/2013